The old Grove Drugstore got it’s start as the Morley Brothers Drugstore back in 1871. Vernon Grove bought the business in 1933 and his tall, brightly lit neon sign was a 6th street landmark for decades (look at all the sexy neon in this old photo). 

However, you might not recognize the sign right away. The city bought the building in the 00s and turned it into the Austin Visitor Center. They did their best to repurpose the original sign, and it’s still there.